Blogs/News/PSAs

Ultrafiltration (UF) is a variety of membrane filtration in which forces, such as pressure or concentration gradients, cause separation through the semi-permeable membrane. High molecular weight suspended solids and solutes remain in the so-called retentate while water and low molecular weight solutes pass through the membrane in the permeate (filtrate). The pore size of the ultrafiltration membrane is in the range of 0.01μm ~ 0.05μm, suitable for the separation, concentration and purification of macromolecules and small molecules.

Application of Ceramic ultrafiltration Membrane

UF technology can be used to remove particulates and macromolecules from raw water to produce potable water. It has been used to replace the existing secondary (coagulation, flocculation, sedimentation) and tertiary filtration (sand filtration and chlorination) systems used in water treatment plants or as stand-alone systems in isolated areas with a growing population.

When treating water containing highly suspended solids, primary (screening, flotation and filtration) and some secondary treatments are often used as a pretreatment stage to incorporate ultrafiltration into the process.

When water recovery is simple, very little processing is often required. However, when more in-depth processing is required, industry standard procedures include the use of UF membrane technology, which means removing the physical solids from the water by passing them through a semipermeable membrane. With ultrafiltration, the solids are primarily captured by the filter and discarded.

Circulating water can also be used in a variety of industrial applications including water supply to boilers or cooling towers, pH control, cleaning equipment, hard beds and vehicles, fire fighting, rinsing or process water for manufacturing industrial lines, toilet flushing, dust control, construction activities Mix with concrete.

Ultrafiltration is often used to pre-treat surface water, seawater and bioprocessed municipal water upstream of reverse osmosis plants.

Industries that consume large amounts of water or discharge highly toxic wastewater may use ultrafiltration to recover water.

These include chemicals, steel, plastics and resins, paper and pulp, pharmaceutical and food and beverage industries, including soft drinks and canned foods, and electricity, water and wastewater treatment plants.

Ultrafiltration is used to recycle flow or add value to later products and more. In many cases ultrafiltration (UF) is used for prefiltration in reverse-osmosis plants to protect the reverse-osmosis process. Ultrafiltration is an effective means of reducing the silt density index of water and removing particulates that can foul reverse osmosis membranes.

Features of Ultrafiltration Membrane

Ultrafiltration processes are preferred over traditional treatment methods for the following reasons:

No chemicals required (aside from cleaning)

Constant product quality regardless of feed quality

Compact plant size

Capable of exceeding regulatory standards of water quality, achieving 90-100% pathogen removal.

JIUWU HI-TECH has many unique membrane applications and more than 50 Patents regarding ceramic membrane solution, systems and process applications, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

Reverse osmosis (RO) is a water purification technology that uses a semipermeable membrane to remove ions, molecules, and larger particles from drinking water.

In reverse osmosis, an applied pressure is used to overcome osmotic pressure, a colligative property, that is driven by chemical potential differences of the solvent, a thermodynamic parameter.

The reverse osmosis membrane technology can remove many types of dissolved and suspended species from water, including bacteria, and is used in both industrial processes and the production of potable water. The result is that the solute is retained on the pressurized side of the membrane and the pure solvent is allowed to pass to the other side. To be "selective", this membrane should not allow large molecules or ions through the pores (holes) but should allow smaller components of the solution (such as solvent molecules) to pass freely.

Advantages of ro membrane technology

1. Removes nonionic impurities and dissoved solids (i.e.organics,silica,bacteria)
2. Reduction of hazardous chemical storage and handling associated with ion exchange
3. Reductes loading on ion exchange systems:

Extends run lengths

Extends resin life

Reductions operating costs

Application range of reverse osmosis

Desalination

Dehydration

Concentration

Remove COD/BOD

JIUWU HI-TECH has many unique ceramic membrane applications and more than 50 Patents regarding jiuwu ceramic membranes, systems and process applications, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

Microfiltration (commonly abbreviated to MF) is a type of physical filtration process where a contaminated fluid is passed through a special pore-sized membrane to separate microorganisms and suspended particles from process liquid. MF membrane is commonly used in conjunction with various other separation processes such as ultrafiltration and reverse osmosis to provide a product stream which is free of undesired contaminants.

MF usually serves as a pre-treatment for other separation processes such as ultrafiltration, and a post-treatment for granular media filtration. The typical particle size used for microfiltration ranges from about 0.1 to 10 µm.In terms of approximate molecular weight these membranes can separate macromolecules of molecular weights generally less than 100,000 g/mol.

Applications range:

Remove suspended solid and reduce SS

Remove proteins, polysaccharides, pigments and other impurities

remove bacterial

Dehydration

Concentration

Reduces COD / BOD

JIUWU HI-TECH has many unique china membrane applications and more than 50 Patents regarding ceramic membranes, systems and process applications, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

Ceramic membrane manufactured by JIUWU HI-TECH is used for liquids separation in a cross-flow filtration way which is different from dead-end filtration.

Dead-end filtration means the fluids flow is vertical to the filter surface, and the retained particles rapidly solidify on the surface of the filter to form a so-called filter cake. The pores of the filter are clogged by the filter cake, and the filtration performance is greatly reduced in a short period of time.

Cross flow filtration means turbulence will happen on the surface of the membrane. Therefore, it allows the filtered material to form a filter cake on the filtering surface and keep the flow constant.

JIUWU HI-TECH has many unique membrane applications and more than 50 Patents regarding ceramic membranes, Organic membrane filters, systems and process applications, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

In recent years, the wafer industry has developed rapidly, but at the same time, it also produces a large amount of wastewater. The production wastewater mainly comes from the cleaning process of the polysilicon ingot slicing process. The acid-containing wastewater is produced in the cleaning process after the surface treatment of the polycrystalline silicon ingot with the mixed acid. Since the surface treatment is a mixed acid of nitric acid + hydrofluoric acid, the main pollution in the washing wastewater is pH, fluoride, and nitrate. The organic wastewater is produced in the cleaning process of the sliced polycrystalline silicon wafer. Since the cutting fluid (the main component is polyethylene glycol) and the cut micro powder (the main component is silicon carbide) are used for slicing, the main pollutant in the cleaning wastewater is CODCr and SS.

Polysilicon cutting fluid is made up of polyethylene glycol as the main body and added with various additives. It has a suitable viscosity index, good fluidity, and thermal conductivity, and has good dispersion stability and suspension effect on silicon carbide micropowder. A large amount of waste liquid is generated after cutting, and the waste liquid contains a considerable amount of polycrystalline silicon powder, which has a certain recovery value. The polysilicon powder is recovered by the ceramic membrane separation technology, becoming the so-called cutting fluid recovery. And the site is clean and sanitary, which is in line with the national energy-saving and emission-reduction industry orientation.

Ceramic membrane equipment technology is advanced and mature, with low operating costs and fast return on investment.

Ceramic membrane filtration process can directly deal with the waste liquid containing silicon produced in the solar energy production process, collect silicon, reuse pure water and coolant.

The process can separate silicon powder and pure water, recover over 98% of the silicon powder, reuse more than 90% pure water,reuse about 50% of coolant and shaping agent , which can greatly reduce the load of the sewage station.

The process has the advantages of short process, simple operation, short payback period, and has become the preferred standard process for the benchmarking enterprises in the silicon chip industry.

JIUWU HI-TECH has many unique membrane applications and more than 50 Patents regarding jiuwu ceramic membranes, systems and process applications, ceramic membrane filters, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

Standard discharge, reclaimed water reuse and zero effluent discharge

1. As for paper mill wastewater treatment, pulping wastewater is the most difficult wastewater to be treated in the papermaking industry. The organic pollutants and inorganic salts are high in content, complex in composition, high in hardness, high in costs. The technical staff of JIUWU work with experts from the Institute of Membrane Science and Technology of Nanjing Tech University and develop successfully membrane technology as the core of zero effluent discharge process or zld (zero liquid discharge).

2. Using the process of pretreatment, membrane integration, evaporation crystallization and other related processes turns waste into valuable and achieves the sewage recycle. The project forms a major technological breakthrough in the field of wastewater treatment of pulp and paper.

Application background

Industrial water prices continue to rise

Industrial water intake limit

Increased emission water quality standards (COD, TOC, etc)

Enforcement requirements for environmental protection and water reuse rate, etc.

Large demand for fresh water

Large amount of wastewater discharge

The composition of wastewater is complex, and the content of organic pollutants and inorganic salts is high.

Core advantage of process package

Independent research and development, Global First

Turn waste into treasure and realize 100% full reuse of wastewater

Multiple 10,000-ton demonstration projects

Reuse water, salt, and dry mud

The water quality of the produced water is good and meets the requirements for productive reuse.

zld (zero liquid discharge)

Case

Jiangsu Jiuwu Hitech Co., Ltd has done the largest zero liquid discharge project in paper pulp industry. The project is located in Japanese Oji Paper Co., Ltd. (OJI PAPER) in China, the scale of 40000m3/day of papermaking, pulp wastewater. Main processes include ozone-coupled biofilter (removing COD), the integrated membrane system of uf technology and reverse osmosis, electrodialysis (EDR) concentration system, MVR evaporation crystallization system. Through above-mentioned advanced processing system, the realization of wastewater recycling and zero liquid discharge. The clean water is supplied to the power plant desalination system and the production water system, waste salt is supplied to the Transportation Bureau to do snowmelt agent and chemical raw materials. The project which is the world's largest zero liquid discharge project in paper pulp industry has been stably operating for more than 3 years.

JIUWU HI-TECH has many unique membrane applications and more than 50 Patents regarding ceramic membrane solution, systems and process applications, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

Palm oil is not only the highest yielding cheap vegetable oil on the earth but also a safe raw material for edible oils and daily chemicals, and a raw material for biofuel.

As a raw material for edible vegetable oils, chemical raw materials and biofuel, palm oil has attracted worldwide attention in the process of ecological protection and industrial pollution. As a result, palm oil wastewater treatment also receives much attention.

Palm oil mill effluent (POME)is a yellow liquid with a unique unpleasant smell and comes from oil extraction, cleaning and washing process in the POME factory, which is featured with very high COD and BOD.

Due to its acidic nature (pH 3.4–5.2), high salt and suspended solids, oil and grease, the untreated discharge of POME can result in considerable environmental consequences.

Each ton of palm oil produced emits about 20 tons of high-concentration organic wastewater. When the high-concentration organic wastewater per ton is treated according to the current sewage pond treatment method, it is equivalent to emitting more than 210 million tons of carbon dioxide gas into the atmosphere every year. It's important to solve the problems in palm oil mill effluent treatment.

To achieve environmental requirements and economic challenges, the POME factories are trying to get efficient and return on the investment process.

JIUWU HI-TECH has made a lot of studies and many rich experiences for POME treatment since 2012.

JIUWU HI-TECH offers the solution for POME treatment with an integrated ceramic membrane technology which is a green, friendly environment, economic efficiency and has the following technical benefits:

No discharge of wastewater

Low capital investment ;

Low operation cost;

Oil is concentrated and water is recycled

After integrated process filtration, concentrate including surplus sludge from anaerobic and centrifuge is used as fertilizer for cattle farm and purified water can be used for recycling or the bolier feed water due to salts and organic compounds are removed.

JIUWU HI-TECH has many unique ceramic membrane applications and more than 50 Patents regarding jiuwu ceramic membranes, systems and process applications, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

Although batch processes are currently used, a number of more advanced techniques have been investigated in order to improve the process efficiency of organic acid fermentation. Promising every result must have been achieved using the tangential flow filtration in the continuous fermentation systems.

One of the main advantages of tangential flow filtration is that the higher biomass concentrations are possible because cells are continuously recycled back to the fermentor. A dense population of cells not only accelerates production of lactic acid but also minimizes contamination by foreign microorganisms. Thus high cell density continuous systems could increase the efficiency of lactic acid production. It can also be applied to nictric acid production.

Lactic acid fermentation broth on the main performance of the membrane fouling is

1. Gel polarization fouling of, membrane surface. Lactic acid fermentation broth by centrifuge coarse filters, except for a small amount of mycelium and solids, but also contains a lot of protein, sugar and easily carbonized material. During the membrane filtration process of lactic acid purification, these substances are easily deposited on the membrane surface and formed gel polarization fouling.

1. Membrane pore adsorption, crystallization pollution. Adding an excess of calcium carbonate is to adjust the system pH, in this way, the excess calcium carbonate is easily occurred crystallization within the hole and in the membrane surface. In the actual operation, the pipeline can easily generate a short temperature difference due to the solubility of calcium lactate which is very sensitive to temperature, so the calcium lactate is also vulnerable to precipitation surface or deposition within the membrane hole and in the membrane surface.

In order to remove impurities, ceramic membrane contamination mechanism in the process of lactic acid fermentation comes down to mycelium, protein, sugar and gel polarization pollution caused by carbonized material in the membrane surface of the and crystallization pollution of calcium carbonate - calcium lactate within the hole and membrane surface. Reasonable cleaning membrane procedure is

JIUWU HI-TECH has many unique china membrane applications and more than 50 Patents regarding ceramic membranes, systems and process applications, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

Natural rubber, as initially produced, consists of polymers of the organic compound isoprene, with minor impurities of other organic compounds, plus water.

Currently, rubber is harvested mainly in the form of the latex from the rubber tree or others. The latex is a sticky, milky colloid drawn off by making incisions in the bark and collecting the fluid in vessels in a process called "tapping". The latex then is refined into rubber ready for commercial processing. In major areas, latex is allowed to coagulate in the collection cup. The coagulated lumps are collected and processed into dry forms for marketing.

Natural rubber is used extensively in many applications and products, either alone or in combination with other materials. In most of its useful forms, it has a large stretch ratio and high resilience and is extremely waterproof.

Centrifuged latex is processed into final articles by dipping, extruding, and coating. Different articles have different physical and chemical requirements, which means that the latex used in their manufacture must be modified by the addition of a great variety of substances that give each "formulation" its unique characteristics.

These characteristics are well-specified and must be carefully controlled.

Skim latex is generated during natural rubber processing centrifuged into fresh latex to become concentrated latex. Skim latex is a raw material for producing skim rubber block according to the low content of rubber particles in the range of 4-8% DRC.

Traditionally, skim latex is treated with sulphuric acid to produce cheap, low-quality rubber products of 5% skim rubber content. Not only does this method consume large quantities of the acid, which results in high production cost, more importantly, causing harmful pollutants to the environment.

JIUWU offers a safer, cheaper and greener option to produce skim rubber products of high quality. Through ceramic membrane filtration system, the rubber content in recovered skim latex can be concentrated to more than 15%, the same value in natural rubber without any form of chemical treatment. At the same time, permeate can be recycled.

JIUWU HI-TECH has many unique membrane applications and more than 50 Patents regarding ceramic membranes, Organic membrane filters, systems and process applications, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

CHEESE, MILK, WHEY AND FOOD PROTEIN

Concentrated milk proteins (MPCs) and isolated milk proteins (MPIs) are produced by ceramic membrane filtration system and their dairy proteins are separated from fresh skim milk. They combine rich calcium with good thermal stability and refreshing mouthfeel. They are rich in casein and whey protein in the same proportions as skim milk.

Milk protein concentrates are widely used and are ideal for cheese products, artificial products, dairy drinks, infant nutrition, medical nutrition products (enteral foods), weight management products, powdered dietary supplements and sports nutrition products.

In general, milk protein concentrates provide a concentrated source of protein for sensory and functional properties in the final application process to meet nutritional value. Condensed milk protein serves as an alternative to whole milk powder (WMP), skim milk powder (SMP) and other milk powders, providing the same protein, or as a non-fat milk solid (MSNF). Compared with ordinary milk or skim milk powder, concentrated milk protein with high protein, low lactose characteristics.

The traditional ultra-high temperature sterilization process will destroy many of the active nutrients in milk but low-temperature ceramic membrane filtration technology completely subvert the traditional high-temperature sterilization of milk. The process of milk filtration and clarification is to make natural fresh milk fluid through dairy ceramic membrane technology and avoid heat denaturation of the protein, fully retain 99% of active immunoglobulin and 95% of lactoferrin and a variety of natural vitamins, milk calcium, minerals and trace elements and other nutrients in the state of low temperature and ensuring safety at the same time.

 BACTERIAL REMOVAL FROM MILK

Like many foods, milk and its derivatives provide a suitable environment for spoilage microorganisms. Therefore, pretreatment and temperature, time parameters must be selected to control the growth of microorganisms. Heat treatment and centrifugal sterilization are the traditional methods of reducing total number of bacteria in milk and dairy products, but these methods have their own advantages and disadvantages. Traditional techniques to remove bacteria in milk have more steps and high cost, short life, environmental pollution, inconvenient cleaning. However, the ceramic membrane filtration of milk can well solve these problems.

Membrane separation technology is used to eliminate bacteria in milk, which is based on the fact that the membrane has different material retention rates in various components of milk, including bacteria and spores. Bacteria can make the rejection rate of more than 99%, while casein transmittance can reach about 99%.

Membrane separation technology has a good membrane flux and sterilization effect, can completely remove bacteria in liquid milk, at the same time the flavor of milk has also been improved.

Membrane separation technology for cold sterilization is the method of fresh milk is  preheated to about 50 degrees and skim milk is got through milk cream separation machine. Then on the same day fresh skim milk makes filtration sterilization, combining with high-temperature instantaneous sterilization technology, to access to high quality dairy products. Such low-temperature sterilization retains a good flavor and nutrients, rich aroma.

Moreover, membrane cleaning is much easier to regenerate, so that membrane fouling can be controlled and a higher and more stable membrane flux can be maintained. The use of membrane separation technology for cold sterilization of milk, functional components can be retained during the re-separation activity, is an ideal method of sterilization of milk.

 BACTERIAL REMOVAL FROM WHEY CASEIM

Casein is the basic component df ordinary cheese. In the cheese making process, casein is precipitated by the action of rennet enzymes,and a coagulum is formed consisting of casein,whey proteins,fat,lactose and the minerals of the milk.

Membrane separation technology is used to eliminate bacteria in milk, which is based on the fact that the membrane has different material retention rates in various components of milk, including bacteria and spores.Bacteria can make the rejection rate of more than 99%, while casein transmittance can reach about 99%.

JIUWU HI-TECH has many unique membrane applications and more than 50 Patents regarding ceramic membrane solution, systems and process applications, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

Membrane technology in the chemical industry is applied to brine filtration, natural rubber, polysolicon cutting fluid recovery and lithium recovery from salt lake brines. It can be used in bio-production clarification, edible liquid salt purification, nanofiltration system sulfate removal, primary brine purification and so on. The advantage is that it is environmentally friendly and cost saving. In natural rubber processing, the use of ceramic membrane filtration consumes less quantities of acid and produces less harmful pollutants to the environment. During the process of polysolicon cutting fluid recovery, you only need to spend low operating costs but will receive fast return on investment by using ceramic membrane equipment technology. Besides, the high-precision anti-pollution ultrafiltration membrane is used to purify the brine water, which can remove all solid suspended matter in the brine. With contact equipment, the process is simple and requires no human intervention in the operation. The application of ceramic membrane will help you save costs but gain more profits!

Brine Filtration

JIUWU is the first one to use ceramic membrane in the primary brine purification industry.

Natural Rubber

JIUWU offers a safer, cheaper and greener option to produce skim rubber products of high quality.

Polysilicon Cutting Fluid Recovery

Ceramic membrane can treat the waste liquid silicon produced in the solar energy production process.

Lithium Recovery From Salt Lake Brines

The membrane equipment for the lithium yield can reach 80% which is at the leading level.

JIUWU HI-TECH has many unique ceramic membrane applications and more than 50 Patents regarding jiuwu ceramic membranes, systems and process applications, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

Cephalosporin

Cephalosporin is the second class of β-Lactamase found in nature following by penicillin. Any of various broad-spectrum antibiotics, closely related to the penicillins, which were originally derived from the fungus Cephalosporium acremonium. It has many advantages of high efficiency, broad-spectrum, low toxicity and enzyme-resistance which has been developed four new products to its range. It belongs to superior antibiotics that its application is growing widely. Advanced production technique is very pressing to meet brisk demands of the market both domestically and internationally. Cephalosporin C, or simply as CPC, is the source of original nuclear（7-amino cephalosporanic acid）of various cephalosporium antibiotic.

During the production of CPC, frame filter press, rotate vacuum drum filter are still used as a means of separation to remove protein, mycelium, and solid particulates. The technical means available on site did not achieve satisfactory degrees of separation. Meanwhile, those methods are unable to separate the massive existences of soluble protein, macro-molecule organic matters from the broth. The filtered broth shows not high transmittance with residual insolubility and soluble impurities which would increase the difficulty in the downstream extraction process and have a bad effect on the quality and yield of final product. According to market adjusting, some companies are asked to improve separation performance by means of membrane technology and to reduce the product losses. With the wide applications of ceramic membranes, they will play a significant role in separation and purification of antibiotics.

Three steps are introduced in order to guarantee the yield of CPC in the process of filtrate fermentation broth for the production of CPC by ceramic membranes. Pre-concentration step is made to let feed volume Vo concentrate to Vd and permeates are obtained meanwhile; diafiltration step is to add cleaning agents in the wanted liquids while filtration and effective ingredients are got to reach a high yield ; post-concentration step is to concentrate wanted liquids to Ve aiming to treat residuals conveniently and improve yield further.

Ceramic membrane for fermentation filtration system could intercept protein and solid particulates from the untreated antibiotic fermentation broth. The protein –removing the capability of this technology is 10 times as much as that of the original process, with filtration yield increasing by 6％. The attenuation range of membrane flow rate is narrow and thus a better product quality can be obtained.

The temperature of CPC fermentation broth from the fermented process drops to 10 below zero and it is acidified to pH2.5-3.0 by the use of hydrofluoric acid.

Then CPC clarity is got due to removing mycelium, suspended solids, and macromolecular protein through the filtration process. In the next refining process, macroporous resin adsorption and ion-exchange are applied, and then nanofiltration and reverse osmosis are also used to obtain concentrated CPC.

 Spectinomycin

Spectinomycin is an older antibiotic from S. spectabilis whose structure contains an unusual tricyclic ring. Spectinomycin is sold under the tradename Trobicin among others, is an antibiotic useful for the treatment of gonorrhea infections. It is given by injection into a muscle.

In the process of spectinomycin bio-fermentation, there are many bacteria, protein, macromolecular pigment, insoluble starch and sub-micron particles in the fermentation broth. The presence of these impurities can cause blocking in the post-ion exchange adsorption or pollution in the post-extraction, affect the extraction and purification efficiency and lead to the decline of the quality of follow-up products, and even feed contamination, resulting in product scrap, so industrial production must be separated to remove such impurities.

Clarification fermentation broth is usually done by plate frame filtration, vacuum drum filtration, diatomaceous earth filtration, centrifugation, and other methods.

However, neither of these methods can completely and effectively separate the impurities in the fermentation broth, which can easily cause blockage and frequent replacement of the filter medium, thereby affecting work efficiency.

With many years of experience in filtration and membrane separation technology  in the pharmaceutical industry, ceramic membrane filtration technology and organic membrane filtration technology are successfully applied to fermentation broth clarification process to solve the problem of clarification in the production of fermentation broth which achieves the goal of simplifying process, convenient operation, clean production requirements and development of advanced scientific and technological innovation.

 Erythromycin

Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin and is often used for people who have an allergy to penicillins.

Erythromycin is mainly fermentation production. As the fermentation broth contains a large number of mycelium, protein and polysaccharide material, to the separation and extraction of erythromycin caused difficulties affecting their yield and quality. Therefore, before the separation and extraction of the fermentation broth need pretreatment. At present, a more commonly used method is flocculation and high-speed centrifuge. The former sterilization rates are relatively high, but the removal of proteins and polysaccharides less effective, resulting in a high solution viscosity, affecting the crystallization process of the follow-up; the latter large energy consumption, equipment is expensive, in the actual production is difficult to wider application.

During the production of erythromycin, frame filter press, rotate vacuum drum filter are still used as a means of separation to remove protein, mycelium, and solid particulates. The technical means available on site did not achieve satisfactory degrees of separation. Meanwhile, those methods are unable to separate the massive existences of soluble protein, macro-molecule organic matters from the broth. The filtered broth shows not high transmittance with residual insolubility and soluble impurities which would increase the difficulty in the downstream extraction process and have a bad effect on the quality and yield of final product. According to market adjusting, some companies are asked to improve separation performance by means of membrane technology and to reduce the product losses. With the wide applications of ceramic membranes, they will play a significant role in separation and purification of antibiotics.

Features of ceramic membrane systems

Continuous operation mode, allowing continuous feed, permeate and concentration

Fully automatic control system

Accurate diafiltration process

CIP system

Applicable for filtration at high temperature

Mechanically strong, highly resistant to wide ranges of pH values, and resistant to acids, caustic, organic solvents and strong oxidants;

High concentration factor, low water consumption, and small waste discharge

Integrated Ultrafiltration and Nanofiltration  is a separation in recent decades developed a new technology, better removal of macromolecules such as proteins and polysaccharides. With this technology, the usage of exacting solvent and de-emulsifier will be greatly minimized, reducing the load on the followed high-speed centrifuge, solvent recycles and treatment of waste solids and wastewater. Moreover, NF permeates could be recycled directly as UF diafiltration water, extensively reducing the consumption of water and the load on wastewater treatment.

 Lincomycin

Lincomycin is a lincosamide antibiotic that comes from the actinomycete Streptomyces lincolnensis.

A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom with inversion of chirality

Process

Fermentation pretreatment

Solvent extraction

Bleaching

Crystallization

Drying

Final product

Colistin sulphate

Colistin sulphate, also known as polymyxin E, is an antibiotic produced by certain strains of the bacteria Paenibacillus polymyxa. Colistin sulphate is a mixture of the cyclic polypeptides colistin A and B and belongs to the class of polypeptide antibiotics known as polymyxins. Colistin sulphate is effective against most Gram-negative bacilli.

Colistin sulphate Separation and Purification technology is suitable for industrial production of modern antibiotics using microbial synthesis, which can replace traditional purification technologies such as adsorption, precipitation, solvent extraction and ion exchange.

Separation process provides optimum solutions with the unique characteristics without any chemical reaction, no phase change, does not destroy the biological activity, environment-friendly.

 CLAVULANIC ACID

Clavulanic acid is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor.

In the process of clavulanic acid bio-fermentation, there are many bacteria, protein, macromolecular pigment, insoluble starch and sub-micron particles in the fermentation broth. The presence of these impurities can cause blocking in the post-ion exchange adsorption or pollution in the post-extraction, affect the extraction and purification efficiency and lead to the decline of the quality of follow-up products, and even feed contamination, resulting in product scrap, so industrial production must be separated to remove such impurities.

Clarification fermentation broth is usually done by plate frame filtration, vacuum drum filtration, diatomaceous earth filtration, centrifugation and other methods.

However, neither of these methods can completely and effectively separate the impurities in the fermentation broth, which can easily cause blockage and frequent replacement of the filter medium, thereby affecting work efficiency.

With many years of experience in filtration and membrane separation technology in the pharmaceutical industry, ceramic membrane filtration technology and organic membrane utrafiltration technology are successfully applied to fermentation broth clarification process to solve the problem of clarification in the production of fermentation broth which achieves the goal of simplifying process, convenient operation , clean production requirements and development of advanced scientific and technological innovation.

JIUWU HI-TECH has many unique china membrane applications and more than 50 Patents regarding ceramic membranes, systems and process applications, in areas such as Food & Beverage, Bio-Pharm, Environmental and the Chemical Industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

Membrane filtration principle

Membrane filtration technology is based on a selective filtration through a pressure-driven membrane for sulfate water treatment. The membrane has charged groups that selectively reject multivalent anions such as SO42-. The membrane does not separate monovalent ionic species such as Cl- or CLO3- from the feed solution.

To maximize the membrane area within a compact space, the membranes are packaged as cylindrical elements in a spiral wound configuration.

Feed brine floods the entire feed side of the membrane surface within the membrane element by flowing within a mesh spacer. Brine then permeates through the membrane, where the sulfate is rejected, and flows in a spiral pattern through the permeate carrier, towards the perforated perforated permeate tube.

To achieve the required membrane area, several membrane elements are packed into several high-pressure housing. The high-pressure housings are arranged in series to provide the required number of stages to concentrate the sodium Sulfate solution.

The ceramic membrane filtration unit usually treats dechlorinated depleted brine from the chlor-alkali electrolyzer. It is at this location that athe Na2SO4 concentration is at its highest and the NaCL concentration is at its lowest. Normally only a portion of the dechlorinated brine flow needs to be passed through Sulfate removal system, the remainder bypasses the Sulfate removal unit and is returned to the saturators.

Features:

1. Reduced purge of depleted brine

Substantial costs saving due to less NaCL loss

More Environmental friendly, less effluent

2. No secondary pollution

No need to use BaCl2 reagent which is toxic

No Barium treatment cost

No solid BaSO4 waste

3. No secondary pollution

Lower operating costs

Reduces effluent volume

Full recovery of sulfate and sodium chloride

Proven technology with many references

JIANGSU JIUWU HI-TECH CO. LTD.,founded in 1997, focus on producing ceramic membrane purification for many years. And JIUWU HI-TECH has become a leading company in the membrane separation industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

The alumina abrasive having a microcrystalline structure obtained by the gel method is called the ceramic grains. Through special processing, each grain has thousands of tiny crystals. This structure brings the very good self-sharpness performance of the grains, which can continuously reveal new and sharp cutting edges.

RIKEN RMC Ceramic grains are very dense, rough, strong and sharp. When worn, they will produce a sharp cutting edge similar to the knife edge. Therefore, the ceramic grains will have a lower cutting temperature and lower burnt than the ordinary alumina when sanding hard to sand materials. It can be keeping sharpness for a long time with low loading. So that will bring you less total downtime and longer life.

Ceramic grains products could process into kinds of shapes, like belts, sand discs, sheets. The grains character decide that products have longer sanding life, higher cutting force and higher sanding efficiency performance.

Ceramic abrasive grain belts and sanding discs could bring you rapid cutting on difficult-to-sand materials such as aerospace, aerospace alloys and forged steel. The unique ability of ceramic abrasives increase production and reduces labor costs. RIKEN RMC Ceramic grains products also have a good performance in general sanding in auto repair, steamships, and aluminum alloys.

Ceramic abrasive is a new abrasive with microcrystalline structure prepared by gel sintering. It does not use smelting method and uses Al2O3 below 5 microns. In the presence of acid, some of the oxide is added to produce gelatin, which is made into granules. The raw material is strict, and the content of sodium oxide is less than 5%. It is characterized by non-smelting and crystallization within 3 microns.

Ceramic abrasives are hard and tough. Fine crystal shape can make Abrasives fall off regularly at different levels, make self-sharpening orderly, keep the sharpness of the whole abrasive, and have good processing effect.

Working conditions are equally important. Temperature and pressure are more important. Crystals are destroyed one by one to achieve self-sharpening.

It is first used to coat abrasives, which is 3-5 times higher than ordinary corundum (ordinary 100, zirconium corundum 207, ceramic abrasive 333).

At present, the world famous ceramic abrasives manufacturer include Saint-Gobain, 3M, Tebuck , VSM and Hermes. American 3M company is called "Cubitron", and its maximum crystallization is less than 3 micron.

Norton company is called SG abrasive, its crystal form is several microns; German Hermes company is called CB abrasive, its maximum crystallization is less than 5 microns. The crystal type of CX abrasive in Japan is called 1 micron, but in fact it is less than 3 micron.

We offer different kinds of Station Post Insulator for Substation, Line Post Insulator, Disc Suspension Insulator, Hollow & Bushing Insulator, Composite Insulators etc.such as Circuit Breaker (CB), Post Insulator, Disconnector, Potential Transformer (PT), Surge Arrester, etc.

Contact us get more details about Station Post Insulator, such as TDS, Application Method, OEM etc.

We can supply different type of high voltage ceramic insulators, also customer required.

We offer different kinds of Hollow & Bushing Insulator for Substation, such as Circuit Breaker (CB), GIS, Post Insulator, Disconnector, Potential Transformer (PT), Surge Arrester, etc.

Contact us get more details about Hollow & Bushing Insulator, such as TDS, Application Method, OEM etc.

We can supply different type of Hollow & Bushing Insulator, also customer required.

Background technique of ceramic transformer insulator

Arcing, corona, etc. occur in the device or the end of the hollow core composite sleeve, and the high temperature generated directly acts on the inner wall of the epoxy layer. Or the plasma generated by the arc and the corrosive gas generated by the decomposition of SF6 in the circuit breaker may impinge on the inner wall of the exposed epoxy layer. Polyethylene oxide itself has high temperature ablation resistance, arc resistance and corona resistance, and may cause severe surface ablation and leakage. Therefore, it is necessary to improve the arc resistance of the Hollow & Bushing Insulator.

In the existing science and technology, the fluoroplastic tube is sheathed in the polyethylene oxide/glass fiber composite pipe, thereby utilizing the arc resistance of the fluoroplastic to prevent arc, corona and the like from damaging the inner wall of the hollow composite pipe. However, in this way, its flexibility is poor, the pipe wall is thick, the production is difficult, and the cost is high.

Introduction of Hollow Core Insulators hollow insulator:

Hollow & Bushing Insulator plays an important role in insulation, support, etc. in outdoor power stations, substation and electrical equipment, or as a component of electrical equipment for power equipment. It is usually made of glass fiber hollow-wound tube, upper and lower flanges and silicone rubber shed, which provides support and insulation for wires and electrical equipment, or acts as external insulation for electric equipment, bearing external forces such as bending and stretching.

Structure of hollow porcelain insulator:

The Hollow & Bushing Insulator consists of an insulated mandrel inner cylinder, a tip flange, and a silicone rubber umbrella sleeve. The silicone rubber umbrella sleeve is formed by connecting two or more silicone rubber umbrella sleeve segments, and the connection structure between the adjacent two silicone rubber umbrella sleeve segments is a stepped lap joint structure, which increases the lap joint area. When the silicone rubber umbrella sleeve is subjected to the axial tensile force, the joint strength between the two mold umbrella sleeves is strengthened, the electrical performance of the hollow composite insulator is ensured, and the service life is prolonged.

Ceramic Nanofiltration membrane is relatively recent membrane filtration system, with the purpose of softening and removal of disinfection by-product precursors such as natural organic matter and synthetic organic matter. More ultrafiltration membrane system details here!

CHARACTERISTICS OF NANOFILTRATION CERAMIC MEMBRANE ELEMENT

Chemical, mechanical and thermal stability

Ability of steam sterilization and back flushing

High abrasion resistance

High fluxes

High durability

Bacteria resistance

Possibility of regeneration

Dry storage after cleaning

OVER VIEW OF NANOFILTRATION CERAMIC MEMBRANE ELEMENT

Ceramic nanofiltration membrane is widely used in petroleum and chemical industry, medicine, metallurgy and other processes involving harsh systems due to its unique thermal stability and chemical stability, resistance to organic solvents, disinfection, regeneration, and backwashing. In the industrial field, ceramic membrane system has become one of the fastest growing and most promising membrane materials in the membrane field.

1. Nanofiltration technology

Nanofiltration membrane technology is a new type of pressure-driven separation technology between ultrafiltration and reverse osmosis. It can not only effectively separate the relative molecular mass of 200-1000 by sieving, but also generate the Donnan effect by electrostatic action, with high removal rate for divalent and high valence ions.

In recent years, nanofiltration technology has gradually occupied an important position in the petrochemical, food processing, wastewater treatment, medical technology, and energy industries, and is a common technology for achieving sustainable development.

2. Ceramic nanofiltration membrane

Nanofiltration membrane materials are a key core of nanofiltration technology. Ceramic nanofiltration membrane has excellent thermal stability, chemical stability, high mechanical strength, acid and alkali resistance, microbial erosion, chlorine and other oxidizing substances, anti-pollution, etc. It has become the fastest growing and most developed in the membrane field and one of the prospective membrane materials.

APPLICATION OF NANOFILTRATION CERAMIC MEMBRANE ELEMENT

1. Chemical industry (membrane technology in the chemical industry)

a. Application in catalyst recovery in the petrochemical industry

In petrochemical and chemical production, the application of the catalyst is very extensive, and it is generally necessary to separate the product and the catalyst after the reaction. Ceramic nanofiltration membrane has good heat resistance, chemical solvent resistance, and good mechanical strength. It adopts cross-flow filtration method in catalytic reaction solid-liquid separation and has the advantages of high-temperature resistance, acid and alkali resistance, solvent resistance, etc. The coupling can fully improve the efficiency of the reactor, high separation precision, and can separate the nano-scale catalyst.

b. Application in brine purification in the field of the chlor-alkali chemical industry

Ceramic nanofiltration membrane has excellent performance such as pollution resistance and long life and is widely used in the field of chlor-alkali chemical industry. Using efficient "cross-flow" filtration, it is difficult to achieve results and advantages with other refining and filtration technologies.

2. Fine separation of medicine

Compared with traditional organic membranes, ceramic composite nanofiltration membranes have the unique advantages of high separation precision, guaranteed filtrate quality, high flux filtration, high product yield, low wastewater, low cleaning frequency and no need for additives. It can realize desalting and pre-concentration of target products and has been successfully applied to biological enterprises such as glutamic acid, citric acid, itaconic acid, and vitamin C.

3. Environmental water treatment (water filtration membrane)

The integrated process with ceramic membrane + organic membrane as the core is widely used in: oily water filtration system, metallurgical wastewater treatment, chemical wastewater treatment, paper mill wastewater treatment, large-scale pure water and ultrapure water preparation, zero discharge of power plant brine.

4. Gas purification

The integrated process technology with ceramic nanofiltration membrane as the core has the unique advantages of high separation precision, short process, acid and alkali resistance, high-temperature resistance and pollution resistance. It is widely used in industrial flue gas desulfurization, blast furnace solid-gas separation and automobile exhaust gas treatment. Wait.

5. New materials field

The ceramic nanofiltration membrane can effectively remove impurity ions in the slurry and efficiently prepare ultrafine ultra-pure nano-powder. At present, it has been applied to the purification of nano-powders such as nano-catalysts and ultra-pure non-ferrous metals. It can also be used in the purification process of nano-materials such as lithium batteries and graphene so that the impurity components in the production process can be removed in time, which is beneficial to the improvement of product yield.

Ceramic membranes (Porous Ceramic Membrane & tubular ceramic membrane) are available for microfiltration, ultrafiltration and nanofiltration as single-channel or multiple-channel elements with channel diameters between 2 and 16mm.

Contact us now for more details about China membrane and the ceramic membrane price!

The principle of porous tubular ceramic membrane

The principle of the filtration is based on two opposing effects: on the one hand, the particles are transported by the filtration flux to the membrane where they cause an increase in concentration; on the other hand, concentration differences are again reduced by the turbulence of the cross-flow and by Brownian motion of the particles. Ceramic membrane separation has greatly improved work efficiency and quality.  

During filtration by means of ceramic membranes made by JIUWU ceramic membrane manufacturer, the medium to be filtered flows through the channels of the membrane support. All particles whose size exceeds the pore radius of the membrane are retained. The particles /molecules build up in the concentrate. The filtrate permeates through the pores and depending on the procedure is subjected to subsequent process stages. This filtering method is also called "cross-flow filtration" or "dynamic filtration". Cross-flow management can achieve stable fluxes. Still, the cleaning of cross-flow installations needs to be applied from time to time. Cleaning is performed by means of backward flushing or chemical cleaning. There are various ceramic membranes for water treatment in the market, while JIUWU ceramic membranes for wastewater treatment perform very well. Learn more about  pilot ceramic membrane technology and ceramic membrane design here! 

The principle of cross-flow filtration in porous tubular ceramic membrane

Skid-mounted device (Ceramic Membrane Filtration System) effectively allocates and stores machine for process and modular systems in the field of solid-liquid separation. A CMF skid-mounted device is designed by order and fully optimized as process flow, which includes CMF unit, power part, control part and supporting pipelines, valves and instruments. The device can be designed as a containerized device.