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antibiotics (3)

The Origin of Wells

A well is an engineering structure used primarily for the extraction of groundwater. It diversifies from vertical, oblique to various combinations of directions based on the distribution of underground water and the lithologic structure of the aquifer, among which the general one is vertical. Versatile as it is, a well is applicable for water intake, drainage, injection and storage thereby attaching great significance to the development of human civilization.

 

The water well engineering signifies the development of human civilization by breaking through the activity limitation that long before wells only could people live by water with surface water or springs available. China is one of the earliest countries in the world to exploit and utilize groundwater, which is verified by the water well of the Hemudu archaeological site in Yuyao, Zhejiang, the oldest ancient water well discovered in China dating back to about 5700 years ago. It is a delicate square wooden well with 1.35 m depth and 2 m sides, which gives rise to the hypothesis of an earlier original one.

 

Thewater well engineeringcan construct the dewatering well, the water and ground source heat pump well and install the water air conditioning and the cooler, the machine drilling deep well (the factory specialized well), the stone well, the drinking water well, the farmland well. It covers the foundation dewatering treatment, the old well renewal, the deep water pump maintenance, the dewatering of large-scale foundation pits, sewage pipes and tunnels and the water supply of factory production, mechanical cooling and domestic usage. Dewatering methods adopted are the tube well dewatering, the deep well dewatering and the light well-point dewatering.

 

 

We have a strong technical force, sophisticated modern equipment and rich experience in production and construction. As a mining drilling equipment manufacturers, we provide one-stop service for drilling, drilling engineering, equipment supply, supporting installation, commissioning and after-sales service.

 

Leading high and new technology in China: We start the service of drilling to rig manufacturing industry. It is a company that sells multi-functional drilling rig with hydraulic hole, anchoring drilling machine, well drilling rig, all hydraulic integrated drilling rig and a series of heavy driving machines in China.

 

Excellent technical talents: As a professional ABT drilling equipment company, it focuses on hot spring well and other new products, new technologies, new processes and new equipment, providing a strong guarantee for follow-up services.

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Antibiotics Fermentation Broth Clarification

Cephalosporin

Cephalosporin is the second class of β-Lactamase found in nature following by penicillin. Any of various broad-spectrum antibiotics, closely related to the penicillins, which were originally derived from the fungus Cephalosporium acremonium. It has many advantages of high efficiency, broad-spectrum, low toxicity and enzyme-resistance which has been developed four new products to its range. It belongs to superior antibiotics that its application is growing widely. Advanced production technique is very pressing to meet brisk demands of the market both domestically and internationally. Cephalosporin C, or simply as CPC, is the source of original nuclear(7-amino cephalosporanic acid)of various cephalosporium antibiotic.

 

During the production of CPC, frame filter press, rotate vacuum drum filter are still used as a means of separation to remove protein, mycelium, and solid particulates. The technical means available on site did not achieve satisfactory degrees of separation. Meanwhile, those methods are unable to separate the massive existences of soluble protein, macro-molecule organic matters from the broth. The filtered broth shows not high transmittance with residual insolubility and soluble impurities which would increase the difficulty in the downstream extraction process and have a bad effect on the quality and yield of final product. According to market adjusting, some companies are asked to improve separation performance by means of membrane technology and to reduce the product losses. With the wide applications of ceramic membranes, they will play a significant role in separation and purification of antibiotics.

 

Three steps are introduced in order to guarantee the yield of CPC in the process of filtrate fermentation broth for the production of CPC by ceramic membranes. Pre-concentration step is made to let feed volume Vo concentrate to Vd and permeates are obtained meanwhile; diafiltration step is to add cleaning agents in the wanted liquids while filtration and effective ingredients are got to reach a high yield ; post-concentration step is to concentrate wanted liquids to Ve aiming to treat residuals conveniently and improve yield further.

 

Ceramic membrane filtration system could intercept protein and solid particulates from the untreated antibiotic fermentation broth. The protein –removing the capability of this technology is 10 times as much as that of the original process, with filtration yield increasing by 6%. The attenuation range of membrane flow rate is narrow and thus a better product quality can be obtained.

 

The temperature of CPC fermentation broth from the fermented process drops to 10 below zero and it is acidified to pH2.5-3.0 by the use of hydrofluoric acid.

 

Then CPC clarity is got due to removing mycelium, suspended solids, and macromolecular protein through the filtration process. In the next refining process, macroporous resin adsorption and ion-exchange are applied, and then nanofiltration and reverse osmosis are also used to obtain concentrated CPC.

 

Founded in 1997, Jiangsu Jiuwu Hi Tech Co. Ltd. is one of the most professional and reliable ceramic membrane manufacturer in China. Owning n more than 50 patents regarding ceramic membranes, Jiuwu Hi-Tech supplies a series of high-quality ceramic membrane of microfiltration, ultrafiltration and nanofiltration, ceramic membrane module, membrane testing machine and professional ceramic membrane filtration system for industrial use, including solid-liquid separation in food and beverage, biotechnology, water treatment, chemcial industry, etc.

 

Jiuwu Hi-Tech is working to provide clients with the best quality ceramic membrane products and services.

 

Organic Membrane Filtration System

OMS skid-mounted (Organic Membrane Filters System) refers to a form of overall combination of equipment frame and whole equipment. Organic membrane system means that a group of equipment is fixed on the chassis and can be used after moving. It is not necessary to install valves and instruments in the middle, and it can be used by directly connecting the pipelines. OMS skid-mounted device is widely used in reverse osmosis (RO), Nanofiltration (NF), Ultrafiltration (UF) and Microfiltration (MF). OMS skid-mounted device is customized design to evaluate the performance applied in RO, NF, UF& MF.8466644255?profile=original

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Degreasing Liquid Treatment

Degreasing process is a necessary step before any other processing in mechanical industry, in the steel industry and generally speaking in the transformation of raw materials.

 

Degreasing treatment is performed with aid of an aqueous solution containing detergents.

 

The detergents emulsify oil present on the material to be treated; for this reason, oil concentration tends to increase in degreasing baths until the need for renewal and/or replacement, to avoid loss of efficacy.

 

Using ceramic membrane technology, there has two fluids, one is permeated which is constituted by water and detergents present in the original bath, the other is concentrate which contains oils and suspended solids and that is back to oil removal tank. After ceramic membrane treatment, the concentration of oil in the degreasing tank can be maintained at a low and very stable concentration range, the quality of the cleaned steel plate is uniform. The emulsion oil in the waste liquid is subjected to demulsification to reduce the amount of surfactant used in the cleaning solution.

 

Separation principle

Selecting the appropriate ceramic membrane filtration precision, by utilizing the characteristics that oil molecules and water molecules differ by tens of times in size and hydrophilic membrane surface properties of ceramic membrane, oil molecules can be effectively rejected, and water, degreasing bath, and surfactant small molecules can be recycled through the membrane surface. The degreasing bath is concentrated by the ceramic membrane system, and the volume of the discharged waste liquid is greatly reduced.

 

Technical benefits

  1. Oil is removed and decreasing baths can be recycled ;
  2. Costs of adding chemicals are significantly reduced;
  3. The usage of surfactant is greatly reduced because of SS removal ;
  4. Regeneration period is prolonged to 6 months or more ;
  5. Subsequent wastewater treatment cost is decreased ;
  6. Longer service life, lower operating pressure and lower energy consumption;
  7. Simple, compact, fully PLC control
  8. Ceramic membrane has excellent chemical resistance, high-temperature resistance and high separation precision

 

JIANGSU JIUWU HI-TECH CO. LTD.,founded in 1997, focus on producing ceramic membrane purification for many years. And JIUWU HI-TECH has become a leading company in the membrane separation industry. We sincerely invite and welcome people from all around the world to invest and create more values together.

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