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Antibiotice purification; Peptide antibiotic synthesis; Enzyme-catalyzed reaction; Chromatographic separation

Modern biopharmaceutical technologies typically of decolorization resin use biological microbial fermentation processes, enzyme-catalyzed reactions, or biologically metabolites obtained by cell culture. Biosynthesis technology can produce many active substances, such as antibodies, antibiotics, etc., but the concentration of biologically active substances is very low, and some is easy to be inactivate, the content of impurities is very high, and many impurities and targets have similar physical and chemical properties, which result Separation and purification difficult.

Sunresin's large pharmaceutical research and development department has proposed different solutions to various problems arising in the biopharmaceutical process through an in-depth understanding of the upstream and downstream industries of biopharmaceuticals. So far, many of our products have been successfully used in the Chinese market.

Our Advantages

Upstream and downstream multi-point solutions for the biopharmaceutical industry

High-standard resin production line special for the pharmaceutical industry

Technical supporting

Our Technique for Bio-pharmaceutical & Life Science

Peptide antibiotic synthesis--solid phase peptide synthesis

The initial peptide antibiotics are also biosynthesized and extracted from the culture of polymyxa or aeruginosa.

Another synthetic method of peptides is chemical synthesis, which is divided into liquid phase chemical synthesis and solid phase chemical synthesis. The liquid phase method is mainly used for the synthesis of short peptides. The solid phase synthesis method can be used to prepare long-chain peptides, cyclic peptides, and complex Peptide.

Enzyme-catalyzed reaction--immobilized enzyme carrier

The enzyme immobilization technique is to immobilize the free enzyme on a solid support by physical or chemical means, and it needs to keep the same activity as the free enzyme.

Bio-pharmaceuticals separation--Ion exchange and adsorption Resin & system

Ion learning exchange and adsorption method is a cost-efficient separation technique that has been widely used in the pharmaceutical industry. It is primarily a way to achieve separation and purification on a large scale with ion exchange systems with complex and designable ion exchange resins. It removes impurities, concentrates the target, and produces highly pure pharmaceuticals.

Chromatographic separation--chromatography media

Separation of pharmaceuticals is often a very complex process, especially for substances with similar structures, such as isomers. At this time, it is necessary to perform high-purity pharmaceutical by means of chromatography separation.

Sunresin Techniques used in Bio-pharmaceutical Industry

Antibiotics Purification

Separation technique based on ion exchange & adsorbent system, for CephalosporinsC, aminoglycoside antibiotic, tocopherol, Polypeptide and proteins purification.

Immobilized Enzyme Carrier

As carrier for Enzyme-catalyzed Reaction, applied in manufacturing of 7ACA、6APA、7ADCA and amino acid.

Solid Phase Peptide Synthesis

Peptide antibiotics could be synthesized by SPPS.

Chromatography Media

Chromatography Separation is especially for substances with similar structures, such as isomers.